ALS/SMA S2B subnetwork

Biological Networks

ALS/SMA S2B subnetwork

Biological Networks

As siblings might have a physical resemblance because they share a genetic background, diseases with similar symptoms are known to share affected genes. Cellular networks enable us to map genes that collaborate in certain functions and additionally, explore how are they are perturbed when some partner gene is missing. We aim to create tools that explore particular disease-related networks to identify which are the genes associated with the pathological origin of both diseases simultaneously. Furthermore, we will search for diseases with already identified therapies and check if the gene targeted by this drug is associated with other diseases at the same time, in which case we can propose this drug for treatment of both diseases. Consequently, the proposed tools can enhance our understanding of human diseases and have a direct impact on drug discovery and therefore on patient life quality.